Lee Sang-il이상일

Career

• Completed residency training in Internal Medicine at Jeonbuk National University Hospital
• Completed fellowship training in Rheumatology at Jeonbuk National University Hospital
• Professor of Rheumatology at Jeonbuk National University Hospital
• Visiting Professor of Rheumatology at San Diego State University, California, USA
• Current: Professor of Rheumatology at Gyeongsang National University Hospital
• Current: Director of the Biomedical Research Institute at Gyeongsang National University Hospital
• Current: Head of the Research-Centered Hospital Project Group at Gyeongsang National University Hospital (gene and cell fusion-based tissue regeneration/immunomodulatory therapeutics)
• Current: Head of the Open Laboratory Specialized in Infectious Diseases designated by the Korea Health Industry Development Institute at Gyeongsang National University Hospital
• Current: Professor in charge of the Innovative Rheumatology Research Laboratory at Gyeongsang National University Hospital
• Current: Member of the Cell Therapy Expert Committee of the Advanced Regenerative Medicine Review Committee
• Current: Editorial Board Member of Frontiers in Immunology
• Awards: Outstanding Resident, Jeonbuk National University Hospital (1999); Best Paper Award, Korean College of Rheumatology (2009, 2013); Best Oral Presentation Award, Korean College of Rheumatology (2010)
• Selected publications
• The Microbiome in Systemic Sclerosis: Pathophysiology and Therapeutic Potential. Int. J. Mol. Sci. 2022
• Lessons from the Success and Failure of Targeted Drugs for Rheumatoid Arthritis: Perspectives for Effective Basic and Translational Research. Immune Network 2022
• Lymph node-fibroblastic reticular cells regulate differentiation and function of CD4 T cells via CD25. Journal of Experimental Medicine 2022
• Chronic inflammation-induced senescence impairs immunomodulatory properties of synovial fluid mesenchymal stem cells in rheumatoid arthritis. Stem Cell Research & Therapy 2021
• Differences in Clinical and Dietary Characteristics, Serum Adipokine Levels, and Metabolomic Profiles between Early- and Late-Onset Gout. Metabolites 2021
• Butyrate Improves Skin/Lung Fibrosis and Intestinal Dysbiosis in Bleomycin-Induced Mouse Models. Int. J. Mol. Sci. 2021
• Blockade of translationally controlled tumor protein attenuated the aggressiveness of fibroblast-like synoviocytes. Experimental & Molecular Medicine 2021
• Correspondence on ‘2018 update of the EULAR recommendations for the management of hand osteoarthritis’. Annals of the Rheumatic Diseases 2020
• Metabolic and inflammatory links to rotator cuff tear in hand OA. PLOS ONE 2020
• Systemic Sclerosis and Microbiota - Overview of Current Research Trends and Future Perspective. Journal of Rheumatic Diseases 2019
• Myeloid sirtuin 6 deficiency accelerates experimental and human rheumatoid arthritis by enhancing macrophage activation and infiltration into synovium. EBioMedicine 2018
• The association of disease activity, pro-inflammatory cytokines, and neurotrophic factors with depression in patients with rheumatoid arthritis. Brain, Behavior, and Immunity 2018
• Myeloid deletion of SIRT1 suppresses collagen-induced arthritis in mice by modulating dendritic cell maturation. Experimental & Molecular Medicine 2016
• Dysregulated Osteoclastogenesis Is Related to Natural Killer T Cell Dysfunction in Rheumatoid Arthritis. Arthritis & Rheumatology 2015
• Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids attenuates K/BxN serum-transfer arthritis in fat-1 mice. Journal of Nutritional Biochemistry 2015