Disease Description (Causes and Symptoms)
- Definition: A general term for tissue changes caused by granulation tissue formed to fill defects after trauma, surgery, burns, or skin disease, followed by collagen remodeling. Once damaged, the skin does not completely regenerate to its original condition.
- Pathophysiology: Scars form when excessive fibroblast activity and excessive deposition of collagen (mainly type III → type I) occur during wound healing. It usually takes 6 months to 2 years to reach maturity (clinical stabilization).
- Main causes and risk factors:
- Depth, length, width, and direction of the wound (more noticeable when inconsistent with the skin crease lines)
- Skin tension (areas subject to pulling, such as joints and the chest), and areas with frequent movement
- Age (more noticeable in younger people), genetic predisposition, and skin pigmentation (keloids are more common in people with darker skin)
- Blood supply, and ultraviolet exposure
- Symptoms:
- Raised or depressed scars, and widening
- Red or dark-red coloration, itching, and stinging
- Keloid: Thick overgrowth extending beyond the wound margins (common on the chest, earlobes, and shoulders)
- Hypertrophic scar: A raised scar that does not extend beyond the wound margins
- Contracture scar: Functional impairment, such as restricted joint movement, due to adhesion of subcutaneous structures caused by a skin defect
Treatment Methods
- General principles
- Prioritize conservative management before the scar matures (6–12 months, up to 2 years). Consider early treatment when a hypertrophic scar or keloid is suspected.
- Conservative and topical treatment
- Silicone sheets/gels (sheet silicone, silicone ointment): First-line options for improving scar width and coloration
- Pressure therapy (especially after burns): Suppression of tissue remodeling with compression garments and dressings
- Massage, moisturization, and UV protection (to prevent pigmentation and excessive proliferation)
- Injection treatment
- Repeated intralesional corticosteroid injections (e.g., triamcinolone): Standard nonsurgical treatment for keloids and hypertrophic scars
- Combination therapy: Steroids + 5-FU, steroids + laser, and other combinations may be used depending on the case
- Physical and laser treatment
- Vascular lasers (PDL), fractional lasers, and others: Improvement of redness and surface texture
- Radiation therapy (as an adjunct for recurrent keloids after surgery): Used selectively; its advantages and disadvantages must be evaluated
- Cryotherapy: May be used for small keloids or hypertrophic scars
- Surgical treatment
- Scar excision and resuturing: Intended to change the direction or reduce the width of the scar (the risk of recurrence is increased when keloids are treated with surgery alone)
- Contracture scars: Skin grafting (split-thickness/full-thickness), flap surgery, and use of tissue expanders
- Combining postoperative adjunctive treatments (steroid injections, silicone sheets, compression, radiation, and others) can reduce the recurrence rate
- Precautions and side effects
- Steroid injections: Skin atrophy, pigment changes, and risk of local infection
- Surgery: Worsening of the scar (especially in people predisposed to keloids), infection, and pigment abnormalities
- Radiation: Long-term risk of cancer development (use cautiously)
- Timing of treatment
- Early intervention may be necessary before maturation if symptoms such as functional limitation (contracture), pain, or persistent itching are severe
- Surgery for cosmetic reasons should be considered after the scar has matured (usually after 6–12 months)
Checklist Before an Outpatient Visit (Items to Prepare and Example Questions)
- Items to prepare (recommended)
- List of current medications and supplements (including steroids, anticoagulants, and others)
- Records of previous surgeries and treatments (including injections, lasers, and radiation) and the results of related procedures
- When and why the scar developed (trauma, surgery, burns, and others), and photographs (from the initial stage to the present)
- Record of symptom changes (size, color, itching, pain, and functional limitations) and factors that worsen symptoms
- Allergies and underlying conditions (diabetes, blood disorders, pregnancy status, and others)
- Key information to tell the doctor during the outpatient visit
- The date the scar first developed and its progression (patterns of increase or decrease)
- Response to previous treatments (whether they were effective and whether there were side effects)
- Functional limitations caused by the scar (such as problems with joint range of motion)
- Pigment changes in the skin around the scar, and whether there is discharge or bleeding
Examples of General Questions to Ask the Doctor
- "How can you tell whether this scar is a keloid or a hypertrophic scar?"
- "What treatment options do you recommend, and what level of improvement can be expected from each treatment?"
- "What are the side effects of injections (triamcinolone), and how many treatments are usually needed?"
- "If I undergo surgery, how likely is the scar to recur, and what can be done to reduce the risk of recurrence?"
- "Are there any precautions I should take in daily life or at work during scar treatment?"
Examples of Condition-Specific Questions
- "This scar has restricted my joint movement. Will I need a skin graft or flap surgery, and what will the expected recovery process be?"
- "The keloid has recurred several times after excision in the same area. Do you recommend radiation as an adjunctive treatment? What are its advantages and disadvantages?"
(Summary) A scar is a tissue change resulting from the natural healing process and usually matures over 6 months to 2 years. There are various options, ranging from conservative treatments (silicone, compression, and UV protection) to injections, lasers, surgery, flaps, and combined radiation therapy. The choice of treatment depends on the type of scar (hypertrophic scar vs. keloid vs. contracture), its location, its functional impact, the patient's preferences, and previous treatment responses.









