Disease Description (Causes and Symptoms)
- Definition: A clinical and general term referring to a series of uncomfortable symptoms that occur with prolonged exposure to an air-conditioned indoor environment. Strictly speaking, it is a syndrome-like pattern caused by environmental exposure rather than the name of a single disease.
- Causes and pathophysiology: Differences between indoor and outdoor temperatures and prolonged exposure to cold disrupt the balance of the autonomic nervous system, causing peripheral vasoconstriction and changes in blood-flow distribution. This can result in decreased cerebral blood flow, changes in gastrointestinal motility, and an imbalance in muscle contraction. People with underlying conditions such as hypertension, diabetes, cardiopulmonary disease, or arthritis are more vulnerable.
- Main symptoms: Upper respiratory symptoms such as sneezing, nasal congestion, and runny nose; headache; malaise (fatigue); muscle pain; indigestion, abdominal discomfort, and diarrhea; and cold sensations or palpitations in the hands, feet, or face. Symptoms generally improve when the air-conditioned environment is improved.
- Differential diagnosis: Common cold (viral upper respiratory tract infection), allergic rhinitis, gastrointestinal disease, legionellosis (an air-conditioning-related infection; suspected in cases of high fever, severe cough, or systemic symptoms), chronic fatigue syndrome, and others.
Treatment Methods
- Fundamental treatment: Most symptoms improve by adjusting indoor temperature and humidity and reducing exposure time.
- Maintaining the difference between indoor and outdoor temperatures at around 5℃ is recommended, and the difference should not exceed 8℃.
- Examples of the recommendations provided: When the outdoor temperature is 23℃ or lower, set the indoor temperature 1℃ lower; when the outdoor temperature is 26–27℃, set it 2℃ lower; when the outdoor temperature is 28–29℃, set it 3℃ lower, and so on (adjust according to the situation).
- Symptom-relief medications: Use short-term symptomatic treatment when necessary.
- Symptom-specific medications such as nasal decongestants and antihistamines (rhinitis and sneezing), antipyretic analgesics (headache and muscle pain), and digestive medicines and antidiarrheals (indigestion and diarrhea).
- Check for interactions with medications for underlying conditions before taking them.
- Procedures/surgery: Not applicable (generally improves with noninvasive management).
- Lifestyle management and self-care
- Relieve muscle tension through regular fluid intake, sufficient rest, and light stretching.
- Wear a light outer garment to maintain body temperature during prolonged exposure to air conditioning.
- Minimize the risk of bacteria and mold through ventilation and management of air-conditioner filters and cooling water.
- Precautions
- Visit a medical institution immediately in the event of high fever, persistent cough, difficulty breathing, severe muscle pain, or worsening or prolonged symptoms.
- If you are immunocompromised or have chronic cardiopulmonary disease, early medical evaluation is recommended when symptoms occur rather than neglecting them and expecting them to resolve on their own.
- Risk of complications
- Complications are generally rare, but inadequate management may worsen existing chronic diseases (cardiovascular or respiratory diseases), and air-conditioning-related infections (e.g., legionellosis) may have a severe course.
Outpatient Visit Checkpoints (Items to Prepare and Example Questions)
- Items to prepare
- A list of medications currently being taken (including prescription drugs, over-the-counter medicines, herbal medicines, and nutritional supplements)
- Past medical history (hypertension, diabetes, heart disease, asthma, etc.) and recent relevant test results (blood pressure, blood glucose, electrocardiogram, chest imaging, etc.)
- A record of when the symptoms began and how long they lasted; symptom patterns (the environments in which they worsen or improve); differences between indoor and outdoor temperatures; and the work environment (such as the duration of air-conditioner use)
- Temperature records and notes about chest symptoms if severe systemic symptoms such as fever, cough, or difficulty breathing occur
- Things to show the doctor at the outpatient visit
- A symptom diary (when and in what environments symptoms worsen) and the condition of the air-conditioning equipment in use (such as the filter-cleaning schedule)
- Example questions (questions for the patient to write down and bring)
- What criteria distinguish these symptoms from other diseases (such as legionellosis or viral infection)?
- Is there any medication I should start taking right away to relieve my current symptoms?
Examples of General Questions to Ask the Doctor
- What are the side effects and duration of use of this medication (the recommended symptomatic treatment)?
- Is there a risk that my symptoms (or underlying condition) will worsen because of the air-conditioned environment?
- If the symptoms do not disappear or recur, what additional tests should I undergo?
- Is there a specific recommended range for managing the indoor temperature in daily life?
Examples of Disease-Specific Questions
- I have hypertension (or diabetes, etc.). What specific measures can I take to reduce the effects of an air-conditioned environment on my blood pressure (blood glucose)?
- If the symptoms persist or are accompanied by fever or respiratory symptoms, should an air-conditioning-related infection such as legionellosis be suspected? What tests (such as lung imaging, blood tests, or sputum tests) should I undergo?




